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GC-rich Sequence Elements Recruit Polycomb Repressive Complex 2 (PRC2) in ES cells

ChEBI2010-11-23 更新2026-07-21 收录

表观遗传调控

干细胞基因组学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-25197 数据链接链接失效反馈

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GC-rich Sequence Elements Recruit Polycomb Repressive Complex 2 (PRC2) in ES cells

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创建时间：

2010-11-23

R-loop研究

表观遗传调控

Strand asymmetry in the distribution of guanines and cytosines, measured by GC skew, predisposes DNA sequences towards R-loop formation upon transcription. Previous work revealed that GC skew and R-lo

NIAID Data Ecosystem20

RNA-Seq of adenomas from Apc-Min mice with additional Tet1 and Tdg mutations

肠道肿瘤转录组学

表观遗传调控

Aberrant DNA methylation is frequently observed in colorectal cancer (CRC), but the underlying mechanisms and pathological consequences are poorly understood. Ten-Eleven Translocation (TET) dioxygena

NIAID Data Ecosystem00

Genome-wide analysis of histone H3 acetylation levels of wild type, hda6, hdc1, and hda19 in short day conditions [ChIP-seq]

组蛋白H3乙酰化修饰

表观遗传调控

To investigate whether the expression of upregulated genes in hdc1 and hda19 is assoiated with histone acetylation levels increased in the hdc1 and hda19 mutants, We carried out ChIP-seq to examine hi

NIAID Data Ecosystem00

DNA dioxygenases Tet2/3 control epithelial differentiation [RNA-seq]

毛囊上皮分化

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Execution of lineage-specific differentiation programs requires tight coordination between many regulators including Ten-eleven translocation (TET) family enzymes catalyzing 5-methylcytosine oxidation

Alliance of Genome Resources00

DNMT3A Reads and Connects Histone H3K36me2 to DNA methylation [RNA-seq]

表观遗传调控

甲基化反应机制

DNA methylation at the 5-position of cytosine (5mC) is a crucial epigenetic mark in regulating biological processes including gene silencing, gene imprinting, and X chromosome inactivation. It has lon

NIAID Data Ecosystem00

GC-rich Sequence Elements Recruit Polycomb Repressive Complex 2 (PRC2) in ES cells

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