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IL-10 regulates generation of both IL-21+IFN-γ+ and IFN-γ+ GC Tfh cells.

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Figshare2016-02-23 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_IL_10_regulates_generation_of_both_IL_21_IFN_947_and_IFN_947_GC_Tfh_cells_/1621790
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Wildtype (WT) and IL-10 deficient mice (IL-10 KO) were infected and 7 days later splenocytes were analyzed by intracellular staining. Contour plots and bar graphs from IL-10 KO and WT controls showing expression of (A) CXCR3 and T-bet, and (B) IL-12Rβ2 in the IFN-γ+ Teff (CD127-) population; (C) IFN-γ and IL-21 in all Teff, and (D) PD-1 and CXCR5 in the IFN-γ+ Teff population. Data are representative of two independent experiments with 3–4 animals per group. Statistical significance from Students t-test. Error bars represent the SEM; ★p ★★p ★★★p
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2016-02-23
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