Catalyst-Free “On-Water” Regio- and Stereospecific Ring-Opening of Spiroaziridine Oxindole: Enantiopure Synthesis of Unsymmetrical 3,3′-Bisindoles
收藏Figshare2017-07-18 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Catalyst-Free_On-Water_Regio-_and_Stereospecific_Ring-Opening_of_Spiroaziridine_Oxindole_Enantiopure_Synthesis_of_Unsymmetrical_3_3_-Bisindoles/5216251
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A catalyst-free water-mediated regio- and stereospecific ring-opening reaction of nonracemic spiroaziridine oxindoles and indoles has been developed with retention of configuration. This method provides direct access to enantiopure 3,3′-mixed bisindoles with excellent yield and enantioselectivity (up to 98% ee).
创建时间:
2017-07-18



