Single cell 'omics resolves transcriptional alterations in Sjogren's Syndrome

This data compares the single cell transcriptional profiles of the minor salivary glands and peripheral blood mononuclear cells (PBMCs) between patients diagnosed with Sjogren's Disease (SjD) and those who do not meet criteria (non-Sjogren's Disease). Portions of this data were reported in two separate publications: Huang & Perez, et al., 2021 Nature Medicine and Yin, et al., 2021, Frontiers in Immunology, although not originally analyzed together. These data were used for additional collaborative publications (Dezfulian, et al., 2023 Cell). Additional single cell data sets were integrated with the existing published datasets, and are now in reporting on compositional differences in the salivary glands of Sjogren's Disease (PMID: 38196575).All patients were consented to NIH IRB... (for more see dbGaP study page.)