Crystal structure of human caspase-1 (Cys285->Ala, Cys362->Ala, Cys364->Ala, Cys397->Ala) in complex with 1-methyl-3-trifluoromethyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid (2-mercapto-ethyl)-amide
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Crystal structure of human caspase-1 (Cys285->Ala, Cys362->Ala, Cys364->Ala, Cys397->Ala) in complex with 1-methyl-3-trifluoromethyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid (2-mercapto-ethyl)-amide Descriptor: 1-METHYL-3-TRIFLUOROMETHYL-1H-THIENO[2,3-C]PYRAZOLE-5-CARBOXYLIC ACID (2-MERCAPTO-ETHYL)-AMIDE, Caspase-1 Authors: Scheer, J.M, Wells, J.A, Romanowski, M.J. Deposit date: 2006-01-18 Release date: 2006-05-16 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3.3 Å) Cite: A common allosteric site and mechanism in caspases Proc.Natl.Acad.Sci.USA, 103, 2006
创建时间:
2006-01-18



