Lrp

This unpublished dataset is based on the [Lrp2 gene](https://www.alliancegenome.org/gene/MGI:95794), which is: Predicted to enable several functions, including PDZ domain binding activity; chaperone binding activity; and insulin-like growth factor I binding activity. Involved in several processes, including circulatory system development; nervous system development; and reproductive structure development. Acts upstream of or within several processes, including animal organ development; circulatory system development; and vitamin metabolic process. Located in several cellular components, including brush border membrane; clathrin-coated pit; and cytoplasmic vesicle. Is expressed in several structures, including egg cylinder; heart and pericardium; metanephros; ureter; and ventricular layer. Used to study Donnai-Barrow syndrome; Fanconi syndrome; and degenerative myopia. Human ortholog(s) of this gene implicated in Donnai-Barrow syndrome and autoimmune thyroiditis. Orthologous to human LRP2.