Crystal structure of PPARgamma with compound BR101549
收藏Protein Data Bank Japan2023-11-22 更新2026-03-21 收录
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Crystal structure of PPARgamma with compound BR101549 Descriptor: Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma, ethyl [2-butyl-6-oxo-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl}-4-(propan-2-yl)-1,6-dihydropyrimidin-5-yl]acetate Authors: Hong, E, Jang, T.H, Chin, J, Kim, K.H, Jung, W, Kim, S.H. Deposit date: 2018-10-19 Release date: 2019-09-11 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.408 Å) Cite: Identification of BR101549 as a lead candidate of non-TZD PPAR gamma agonist for the treatment of type 2 diabetes: Proof-of-concept evaluation and SAR. Bioorg.Med.Chem.Lett., 29, 2019
创建时间：
2018-10-19
