Anatomy of the left ventricle in aortic stenosis and systemic hypertension

Anatomy of the left ventricle (LV) of 109 cardiac magnetic resonance datasets from 91 participants (18 subjects with aortic stenosis had follow-up data after surgical aortic valve replacement). Full details in Differentiating Left Ventricular Remodeling in Aortic Stenosis From Systemic Hypertension (please cite this reference if using this data)The LV end diastolic anatomy was reconstructed from the contours using high order interpolation meshes as described in our previous work. The 109 meshes were then spatially aligned by their centre of mass, and by an orientation defined by their basal plane and the left to right direction set by the centre of mass of the LV and right ventricle. A statistical shape model was then built with a principal component analysis (PCA), finding the modes of anatomical variation of this cohort.Data shared contains:1. AtlasMeshData.zip, where each case of ID "xxx" has1.1 Maskxxx.gipl: The mask of the left ventricular (LV) myocardium and right ventricular blood pool from the short axis magnetic resonance image in end diastole1.2 Maskxxx_mesh files (.exelem and .exnode): the cubic Hermite mesh that was personalised to the anatomy of the left ventricle1.3 Image_Maskxxx_mesh.jpg: image of the overlay between the fitted mesh and the mask of the LV myocardium1.4 Image_Initialization.jpg: image of the overlay between the template LV mesh used for personalization and the mask of the LV myocardium1.5 ImageDistances2ClosestPointMaskxxx_meshxxxxxxxxxx.jpg: image of the distances between the LV mesh and the mask of the LV myocardium (xxxxxxxxxx is a digit encoding for the time when the image was generated)1.6 PersonalizationReportMaskxxx.txt: file with metrics of mesh fitting accuracy and quality1.7 GeometricalMetrics.mat: file with metrics of mesh geometry2. VTKmeshesAlignedDofs.zip: the collection of all the LV shapes in VTK format, after correction of centre of mass and circumferential orientation.3. AtlasModesAS_s4_c5.pdf: illustration of all the 18 first modes of anatomical variation, together with the box-plot of the differences between experimental groups.

本研究对109位参与者（其中18位患有主动脉瓣狭窄且在主动脉瓣置换术后有随访数据）的109个心脏磁共振数据集的左心室（LV）解剖结构进行了分析。详细内容请参阅《区分主动脉瓣狭窄与系统性高血压引起的左心室重塑》（请引用此参考文献以使用此数据集）。通过高阶插值网格从轮廓中重建了左心室舒张末期的解剖结构，正如我们先前工作中所述。随后，109个网格根据其质心进行了空间对齐，并通过由基平面和由左心室和右心室质心设定的左右方向定义的方位进行对齐。接着，使用主成分分析（PCA）构建了统计形状模型，找到了该群体解剖变异的模式。共享的数据包括：1. AtlasMeshData.zip，其中每个ID为“xxx”的案例包含：1.1 Maskxxx.gipl：来自舒张末期短轴磁共振图像的左心室（LV）心肌和右心室血池的掩码；1.2 Maskxxx_mesh文件（.exelem和.exnode）：针对左心室解剖结构个性化设计的立方Hermite网格；1.3 Image_Maskxxx_mesh.jpg：拟合网格与左心室心肌掩码的重叠图像；1.4 Image_Initialization.jpg：模板左心室网格用于个性化与左心室心肌掩码的重叠图像；1.5 ImageDistances2ClosestPointMaskxxx_meshxxxxxxxxxx.jpg：左心室网格与左心室心肌掩码之间的距离图像（xxxxxxxxxx是表示图像生成时间的数字编码）；1.6 PersonalizationReportMaskxxx.txt：包含网格拟合精度和质量指标的文件；1.7 GeometricalMetrics.mat：包含网格几何形状指标的文件；2. VTKmeshesAlignedDofs.zip：在纠正质心和周向方位后，所有左心室形状的VTK格式集合；3. AtlasModesAS_s4_c5.pdf：展示了所有18个第一阶解剖变异模式，以及实验组之间差异的箱线图。