The expression profiles of AMG510-resistant cancer cells
收藏NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE178479
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资源简介:
AMG510 is a covalent inhibitor of G12C mutated KRAS. To identify the mechanism of resistance to AMG510, we treated MIA-PaCa2 cells with increasing dose of AMG510 for 2 months and established two population of cells that are resistant to 5 uM AMG510. RNA sequencing was used to extermine the expression profile. MIA-PaCa2 cells were treated with increasing dose of AMG510 for 2 months and established two population of cells that are resistant to 5 uM AMG510. RNA sequencing was used to extermine the expression profiles of the two populations of cells and two untreated control cell populations.
创建时间:
2021-06-21



