Test No. 470: Mammalian Erythrocyte Pig‑a Gene Mutation Assay

Organisation for Economic Co-operation and Development2026-02-07 收录

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This Test Guideline describes an in vivo erythrocyte Pig-a gene mutation assay (hereafter called the Pig-a assay) which uses an endogenous mammalian gene, the phosphatidylinositol glycan class A gene (Pig-a), as a reporter of somatic-cell gene mutation. In vivo gene mutation tests, such as the Pig-a assay, are especially relevant for assessing...