1, Male, 20 y/o, ataxia-telangiectasia. 5, Female, 57 y/o, ductal breast cancer at 52 y/o, non-medullary thyroid cancer at 30 y/o. 7, Female, 47 y/o, ductal breast cancer at 46. 8, Female, 33 y/o, duc
We have developed a model system to generate multiple human leukemias in a single donor’s genetic background. We wanted to better understand the genetic basis of MLL-AML driven by the MLL-AF9 (MA9) on
The aim of this study was to understand why two siblings carrying both the same homozygous causal mutation for the auto-inflammatory disease hyper IgD syndrome show opposite phenotypes, i.e. the first
