Baseline clinical characteristics and demographic information.

IQR: interquartile range; CT: computed tomography; MRI: magnetic resonance imaging; ITD: initial target dose; MMD: maximum maintenance dose.
a Confounders which were included in the Cox proportional hazard models.
b MMD: the data of patients who had treatment failure before being titrated to initial target dose was excluded.
c PDD: prescribed daily dose. The MMDs were adopted as PDDs, and in patients who withdrew before being titrated to ITDs, the maximum doses that had been taken were adopted. DDD: defined daily dose, 1 DDD = 600 mg [CBZ], 1000 mg [VPA], 135 mg [LTG], 170 mg [TPM], 950 mg [OXC]. The principle of establishing the DDDs was to have a similar distribution of PDD/DDD ratios between each AED in pairwise comparison to make it to possible to compare the use conditions of AEDs
Baseline clinical characteristics and demographic information.