NOP10 predicts NSCLC prognosis and its associated small nucleolar RNAs drive proliferation and migration [PSI-seq]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE161231
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资源简介：
Non-coding RNAs are critical players in non-small cell lung cancer (NSCLC). In the present study, we investigate the role of H/ACA box snoRNA and snoRNA-bound ribonucleoproteins (RNP) in the tumorigenesis of NSCLC. We used Psi-Seq to determine the pseudouridylation modification profile of ribosomal RNA in 7 matched tumor and normal samples from paraffin-embedded tissue from non-small cell lung cancer (NSCLC) patients. To further investigate the role of NOP10 we analyzed A549 cell line with CRISPR Cas9 knock out of NOP10.
创建时间：
2021-02-16
