Effects of EEG-guided transcranial alternating current stimulation (tACS) of the cerebellum on motor behavior and electrophysiological activity

Introduction This database includes the raw data linked with the paper “ Effects of EEG-guided transcranial alternating current stimulation (tACS) of the cerebellum on motor behavior and electrophysiological activity” submitted to the NeuroImage journal. In this paper, we reported behavioral and neurophysiological data of healthy adults receiving EEG-guided transcranial alternate current stimulation (tACS) over the cerebellum. Methods Forty-four male and female participants completed a visuomotor task while undergoing either real or sham tACS across two sessions. Critically, EEG activity was recorded before and immediately after the stimulation while participants performed the visuomotor task to assess electrophysiological changes in power spectrum density. Measures of corticospinal excitability and inhibition were collected via transcranial magnetic stimulation (TMS) protocols following each stimulation session. Results (in brief) tACS at IGF enhanced motor precision during challenging task conditions and reduced corticospinal inhibition, without affecting corticospinal excitability. EEG analyses revealed IGF-dependent increases in theta-band power post-stimulation in motor regions, suggesting cross-frequency interactions