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(Diacetoxy)iodobenzene-Mediated Oxidative C–H Amination of Imidazopyridines at Ambient Temperature

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NIAID Data Ecosystem2026-03-10 收录
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(Diacetoxy)­iodobenzene (PIDA)-mediated direct oxidative C–H amination for the synthesis of 3-amino substituted imidazopyridines has been achieved under metal-free conditions at room temperature in short reaction times. This methodology is also applicable for the regioselective amination of indolizines. Experimental results suggest that the reaction likely proceeds through a radical pathway.

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2017-04-10
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