Hivep2

ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; INVOLVED IN positive regulation of transcription by RNA polymerase II; ASSOCIATED WITH autism spectrum disorder (ortholog); autosomal dominant intellectual developmental disorder 13 (ortholog); autosomal dominant intellectual developmental disorder 43 (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine

编码一种表现出DNA结合转录激活剂活性的蛋白质，特异性结合RNA聚合酶II的顺式调控区序列；参与RNA聚合酶II介导的转录正调控；与自闭症谱系障碍（同源）、13号常染色体显性智力发育障碍（同源）、43号常染色体显性智力发育障碍（同源）相关；存在于细胞核质（同源）；与1,1,1-三氯-2,2-双(4-羟基苯基)乙烷、17α-乙炔雌二醇、2,3,7,8-四氯二苯并-对-二噁英相互作用。