Crystal structure of human c-Met kinase domain with its inhibitor
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Crystal structure of human c-Met kinase domain with its inhibitor Descriptor: CHLORIDE ION, Hepatocyte growth factor receptor, N-({4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}carbamothioyl)-2-phenylacetamide Authors: Matsumoto, S, Miyamoto, N, Hirayama, T, Oki, H, Okada, K, Tawada, M, Iwata, H, Miki, H, Nakamura, K, Hori, A, Imamura, S. Deposit date: 2012-08-08 Release date: 2013-08-14 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure-based design, synthesis, and evaluation of imidazo[1,2-b]pyridazine and imidazo[1,2-a]pyridine derivatives as novel dual c-Met and VEGFR2 kinase inhibitors. Bioorg.Med.Chem., 21, 2013
创建时间:
2012-08-08



