Trace element GWAS summary statistics

Trace elements are important for human health but may exert toxic or adverse effects. Mechanisms of uptake, distribution, metabolism, and excretion are partly under genetic control but have not yet been extensively mapped. Here we report a comprehensive multi-element genome-wide association study (GWAS) of 57 essential and non-essential trace elements. This dataset contains GWAS meta-analysis summary statistics for 14 trace elements (aluminium, arsenic, cadmium, chromium, cobalt, copper, lead, manganese, mercury, molybdenum, nickel, selenium, thallium, zinc) measured in up to 6564 whole-blood samples from the Trøndelag Health Study (HUNT), the Norwegian Mother, Father and Child Cohort Study (MoBa) and the Prospective Investigateion of the Vasculature in Uppsala Seniors (PIVUS) study. Further, the dataset contains GWAS summary statistics of 41 additional trace elements (antimony, barium, beryllium, boron, bromine, calcium, cerium, cesium, chlorine, gallium, germanium, gold, holmium, indium, iridium, iron, lanthanum, lithium, magnesium, neodymium, niobium, palladium, phosphorus, platinum, praseodymium, rhenium, rhodium, rubidium, samarium, silicon, silver, strontium, sulfur, tantalum, terbium, tin, tungsten, uranium, vanadium, yttrium, zirconium) measured in up to 2819 whole-blood samples from HUNT.