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In vivo activation of a conserved microRNA program induces robust mammalian heart regeneration

ChEBI2014-11-17 更新2026-07-21 收录

心脏再生

MicroRNA调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-62389 数据链接链接失效反馈

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资源简介：

In vivo activation of a conserved microRNA program induces robust mammalian heart regeneration

应用场景：

创建时间：

2014-11-17

心脏再生

细胞重编程

Reprogramming of cardiac fibroblasts into induced cardiomyocyte-like cells (iCMs) in situ represents a promising strategy for cardiac regeneration. A combination of three cardiac transcription factor

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Telomerase is essential for zebrafish heart regeneration

心脏再生

端粒酶

Unlike human hearts, zebrafish hearts efficiently regenerate after injury. Regeneration is driven by the strong proliferation response of its cardiomyocytes to injury. In this study, we show that acti

干细胞与再生医学数据中心2022-02-20 更新70

H3K27me3 deposition over sarcomeric and cytoskeletal promoters is required for cardiomyocyte cytokinesis and wound invasion during zebrafish heart regeneration [ChIP-seq]

心脏再生

表观遗传学

Deciphering the genetic and epigenetic regulation of injury-induced heart regeneration in organisms capable of robust cardiac renewal represents an attractive inroad towards regenerating the human hea

干细胞与再生医学数据中心2022-02-20 更新60

Anti-miRs Competitively Inhibit microRNAs in Argonaute Complexes

MicroRNA调控

寡核苷酸药物作用机理

MicroRNAs (miRNAs), small RNA molecules that post-transcriptionally regulate mRNA expression, are crucial in diverse developmental and physiological programs and their misregulation can lead to diseas

NIAID Data Ecosystem90

Additional file 8: Table S4. of Small RNA profiling and degradome analysis reveal regulation of microRNA in peanut embryogenesis and early pod development

MicroRNA调控

RT-PCR引物设计

Oligonucleotide primer sequences used for qRT-PCR. (XLS 31 kb)

Figshare2017-03-10 更新70