Human TrkA in complex with the inhibitor AZ-23
收藏Protein Data Bank Japan2023-12-20 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4aoj
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Human TrkA in complex with the inhibitor AZ-23 Descriptor: 5-chloranyl-N2-[(1S)-1-(5-fluoranylpyridin-2-yl)ethyl]-N4-(3-propan-2-yloxy-1H-pyrazol-5-yl)pyrimidine-2,4-diamine, HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR, ZINC ION Authors: Wang, T, Lamb, M.L, Block, M.H, Davies, A.M, Han, Y, Hoffmann, E, Ioannidis, S, Josey, J.A, Liu, Z, Lyne, P.D, MacIntyre, T, Mohr, P.J, Omer, C.A, Sjogren, T, Thress, K, Wang, B, Wang, H, Yu, D, Zhang, H. Deposit date: 2012-03-28 Release date: 2012-08-15 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Discovery of Disubstituted Imidazo[4,5-B]Pyridines and Purines as Potent Trka Inhibitors Acs Med.Chem.Lett., 3, 2012
创建时间:
2012-03-28



