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Expression of Concern: Akt Regulates Drug-Induced Cell Death through Bcl-w Downregulation

Figshare2019-03-19 更新2026-04-29 收录

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https://figshare.com/articles/dataset/Expression_of_Concern_Akt_Regulates_Drug-Induced_Cell_Death_through_Bcl-w_Downregulation/7863635 数据链接链接失效反馈

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Expression of Concern: Akt Regulates Drug-Induced Cell Death through Bcl-w Downregulation

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2019-03-19

细胞分化调控

Akt信号通路

The mechanism by which Akt modulates stem cell homeostasis is still incompletely defined. Here we demonstrate that Akt phosphorylates special AT-rich sequences binding protein 1 (SATB1) at serine 47 a

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FANCI is a negative regulator of Akt activation

Akt信号通路

Fanconi贫血通路

Akt is a critical mediator of the oncogenic PI3K pathway, and its activation is regulated by kinases and phosphatases acting in opposition. We report here the existence of a novel protein complex that

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datasheet3_Quercetin Induces Apoptosis via Downregulation of Vascular Endothelial Growth Factor/Akt Signaling Pathway in Acute Myeloid Leukemia Cells.xlsx

急性髓系白血病

Akt信号通路

Acute myeloid leukemia (AML) is an aggressive haematological malignancy characterized by highly proliferative accumulation of immature and dysfunctional myeloid cells. Quercetin (Qu), one kind of flav

NIAID Data Ecosystem20

RNA-Binding Protein Musashi1 Modulates Glioma Cell Growth through the Post-Transcriptional Regulation of Notch and PI3 Kinase/Akt Signaling Pathways

神经胶质瘤机制

Akt信号通路

Musashi1 (MSI1) is an RNA-binding protein that plays critical roles in nervous-system development and stem-cell self-renewal. Here, we examined its role in the progression of glioma. Short hairpin RNA

Figshare2016-01-18 更新50

Short-term Akt activation in cardiac muscle cells improves contractile dysfunction in failing hearts.. Mus musculus

心脏收缩功能障碍

Akt信号通路

Akt is a serine/threonine protein kinase that is activated by a variety of growth factors or cytokines in a PI3-kinase dependent manner. Using a conditional transgenic system in which Akt signaling ca

NIAID Data Ecosystem40

Expression of Concern: Akt Regulates Drug-Induced Cell Death through Bcl-w Downregulation

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