DTM: dysregulated target molecules Transcription regulators, recognized to be upstream regulators (z-score +-2), with actual fold change, z-score, p-value of overlap and number of downstream effectors
Affected upstream regulators predicted by IPA from differentially expressed genes in SHR-Tti2+/- vs. wild type SHR rats in the hippocampus, liver, muscle and perirenal adipose tissue. Activation Z-sco
*Gene abbreviations are given in Tables S1 and S2. Gene names in Bold indicate increased expression in EAE, normal italic font indicates decreased expression.