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Unconventional role of HMGCS1 in driving pathogenic-Th17 cell immunity and autoimmune diseases

Name: Unconventional role of HMGCS1 in driving pathogenic-Th17 cell immunity and autoimmune diseases
Creator: Medical Research Institute
Published: 2026-06-24T14:55:34+08:00

integrated proteome resources2026-07-03 收录

Th17细胞免疫

自身免疫疾病研究

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https://www.iprox.cn/page/project.html?id=IPX0013229000 数据链接链接失效反馈

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资源简介：

Unconventional role of HMGCS1 in driving pathogenic-Th17 cell immunity and autoimmune diseases

应用场景：

提供机构：

Medical Research Institute

创建时间：

2026-06-24

Th17细胞免疫

植物提取物药效

Naive CD4+ T cells differentiate into effector (Th1, Th2, Th17) cells and immunosuppressive (Treg) cells upon antigenic stimulation in the presence of a specific cytokine milieu. The T cell in vitro c

NIAID Data Ecosystem90

Th17 Cells Are More Protective Than Th1 Cells Against the Intracellular Parasite Trypanosoma cruzi

Th17细胞免疫

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Th17 cells are a subset of CD4+ T cells known to play a central role in the pathogenesis of many autoimmune diseases, as well as in the defense against some extracellular bacteria and fungi. However,

NIAID Data Ecosystem50

Demographics of 1,013 patients who provided informed consent and completed the autoimmune disease questionnaire.

自身免疫疾病研究

患者人口统计学

Demographics of 1,013 patients who provided informed consent and completed the autoimmune disease questionnaire.

NIAID Data Ecosystem30

Autoantibodies are highly prevalent in non-SARS-CoV-2 respiratory infections and critical illness. Autoantibodies are highly prevalent in non-SARS-CoV-2 respiratory infections and critical illness

自身免疫疾病研究

呼吸道感染免疫

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem50

Amount of CD4+ T-lymphocyte subpopulation producing IL-17.

Th17细胞免疫

化合物效力评估

aPMA/IONO = 1 µM/10 µM.bAEA = 2.5 µM.cSR1 = 1 µM.dSR2 = 1 µM.eACEA = 1 µM.fJWH = 1 µM.*Denotes pversus CTRL; # denotes pversus PMA/IONO; § denotes pversus PMA/IONO + AEA; Φ denotes pversus PMA/IONO +

Figshare2015-12-02 更新30

Unconventional role of HMGCS1 in driving pathogenic-Th17 cell immunity and autoimmune diseases

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