Link prediction in multilayered network
收藏Figshare2016-10-21 更新2026-04-08 收录
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Dataset consists of 5 files.<br> First 4 files describe protein-protein interactions(PPI) in homo sapiens. They are obtained from IntAct database(http://www.ebi.ac.uk/intact/).Selected interaction are filtered based on MI score >= 0.45 from IntAct and considered to be highly confident.<br>Protein names are translated to unique Ensemble(http://www.ensembl.org/index.html) gene identifiers (ENSG). 1. Dataset containing expert curated interactions related to Parkinson's disease parkinson_intact_int_PPI.txt<br>2. All highly confident interactions in hs available in IntAct database intact_int.txt<br>3. Aumatically curated interactions related to synaptic activity synapse_intact_int.txt<br>4. Dataset containing expert curated interactions related to Alzheimer's diseasealz_intact_int_PPI.txtThe 5th file describes genes, that are coexpressed in the Alzheimer's patients and healthy individuals.<br>Correlation profiles are calculated using the set of microarray data obtained from ArrayExpress database (https://www.ebi.ac.uk/arrayexpress/). Final coexpression score is calculated by applying Robust Rank Aggregation method to aggregate correlation scores in individual microarray datasets.Coexpression scores are filtered based on pvalue <=0.00001.<br>Gene names are translated to unique Ensemble(http://www.ensembl.org/index.html) gene identifiers (ENSG). alzcoexp_int_31052016.txt
创建时间:
2016-10-21



