Larry True, Eric Deutsch, Laura Pascal, Tracy Sherertz, Laura Walashek, David Campbell, Alvin Liu (2012) CIL:34071, Homo sapiens, endocrine-paracrine cell of prostate gland, basal cell of prostate epithelium, luminal cell of prostate epithelium, blood vessel endothelial cell, perineural cell, sheath cell, leukocyte, prostate stromal cell, smooth muscle cell of prostate. CIL. Dataset

Tissue section of human prostate containing adenocarcinoma that has been immunostained for the cell-surface antigen CD90. Nuclei are stained in blue. This image is part of a large collection of images generated from numerous specimens to characterize the distribution of CD90 in human prostate tissue. It was noted in Liu et al. (Am J Pathol 165 (2004) 1543-1556) that stromal fibromuscular cells associated with primary prostate cancer differ from stromal cells in benign prostate tissue by an increased level of expression of the cell activation molecule, CD90. A summary of the entire data set is provided below.
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<table border="1px">
<tr>
<th>Cell Type</th>
<th>% intense</th>
<th>% equivocal</th>
<th>% none</th>
<th># assays</th>
</tr>

<tr>
<td>Atrophic glands</td>
<td>0</td>
<td>0</td>
<td>100</td>
<td>11</td>
</tr>

<tr>
<td>Hyperplastic glands</td>
<td>0</td>
<td>0</td>
<td>100</td>
<td>11</td>
</tr>

<tr>
<td>Normal glands</td>
<td>0</td>
<td>0</td>
<td>100</td>
<td>11</td>
</tr>

<tr>
<td>Basal Epithelial Cells</td>
<td>0</td>
<td>0</td>
<td>100</td>
<td>11</td>
</tr>

<tr>
<td>Stromal Endothelial Cells</td>
<td>70</td>
<td>1</td>
<td>29</td>
<td>11</td>
</tr>

<tr>
<td>Stromal Fibromuscular Cells</td>
<td>15</td>
<td>0</td>
<td>85</td>
<td>11</td>
</tr>

<tr>
<td>Stromal Nerve Sheath Cells</td>
<td>60</td>
<td>2</td>
<td>38</td>
<td>11</td>
</tr>

<tr>
<td>Stromal Perineural Cells</td>
<td>0</td>
<td>0</td>
<td>100</td>
<td>11</td>
</tr>

<tr>
<td>Gleason Pattern 3</td>
<td>0</td>
<td>0</td>
<td>100</td>
<td>9</td>
</tr>

<tr>
<td>Gleason Pattern 4</td>
<td>0</td>
<td>0</td>
<td>100</td>
<td>6</td>
</tr>

<tr>
<td>Gleason Pattern 5</td>
<td>0</td>
<td>0</td>
<td>100</td>
<td>1</td>
</tr>

</table>

<br />

The table indicates the percent of each cell type with the indicated staining intensity. Staining intensity levels were classified as intense, equivocal (weak or very focal) or none. Not all of the cell types and staining patterns are visible in each image.
<br />
<br />
This image is part of a large collection of immunohistochemistry images of cell-surface antigens generated by the SCGAP Urologic Epithelial Stem Cells (UESC) Project. The overall goal of the project is to characterize and isolate epithelial stem cell populations from two urologic organs, the prostate and bladder. Links are provided below for the UESC Project database, the entire human prostate immunostain summary, the CD90 immunostain summary, and information on the specimen that this image is from. Other images of CD90 human prostate immunostains are accessible following the group link.

人前列腺组织切片，其中含有经免疫染色检测的腺癌细胞表面抗原CD90。细胞核呈蓝色染色。该图像属于由众多样本生成的大量图像集的一部分，旨在描绘CD90在人类前列腺组织中的分布情况。据Liu等人在《美国病理学杂志》第165卷（2004年）第1543-1556页的研究指出，与原发性前列腺癌相关的间质纤维肌细胞在CD90细胞活化分子表达水平上与良性前列腺组织中的间质细胞存在差异。以下是对整个数据集的概述。

<table border="1px">
<tr>
<th>细胞类型</th>
<th>染色强度百分比</th>
<th>可疑百分比</th>
<th>无染色百分比</th>
<th>检测次数</th>
</tr>

<tr>
<td>萎缩腺体</td>
<td>0</td>
<td>0</td>
<td>100</td>
<td>11</td>
</tr>

<tr>
<td>增生腺体</td>
<td>0</td>
<td>0</td>
<td>100</td>
<td>11</td>
</tr>

<tr>
<td>正常腺体</td>
<td>0</td>
<td>0</td>
<td>100</td>
<td>11</td>
</tr>

<tr>
<td>基底层上皮细胞</td>
<td>0</td>
<td>0</td>
<td>100</td>
<td>11</td>
</tr>

<tr>
<td>间质内皮细胞</td>
<td>70</td>
<td>1</td>
<td>29</td>
<td>11</td>
</tr>

<tr>
<td>间质纤维肌细胞</td>
<td>15</td>
<td>0</td>
<td>85</td>
<td>11</td>
</tr>

<tr>
<td>间质神经鞘细胞</td>
<td>60</td>
<td>2</td>
<td>38</td>
<td>11</td>
</tr>

<tr>
<td>间质神经周围细胞</td>
<td>0</td>
<td>0</td>
<td>100</td>
<td>11</td>
</tr>

<tr>
<td> Gleason模式3</td>
<td>0</td>
<td>0</td>
<td>100</td>
<td>9</td>
</tr>

<tr>
<td> Gleason模式4</td>
<td>0</td>
<td>0</td>
<td>100</td>
<td>6</td>
</tr>

<tr>
<td> Gleason模式5</td>
<td>0</td>
<td>0</td>
<td>100</td>
<td>1</td>
</tr>

</table>

该表格显示了每种细胞类型在指定染色强度下的百分比。染色强度水平被划分为强烈、可疑（弱或非常局灶）或无染色。并非每种细胞类型和染色模式在每个图像中均可见。

该图像是SCGAP泌尿上皮干细胞（UESC）项目生成的细胞表面抗原免疫组化图像集的一部分。该项目的总体目标是表征和分离来自两个泌尿器官——前列腺和膀胱的上皮干细胞群体。以下链接提供了UESC项目数据库、整个人类前列腺免疫染色总结、CD90免疫染色总结以及关于该图像来源样本的信息。有关CD90人类前列腺免疫染色的其他图像可通过项目组链接获取。