The crystal structure of the 2009 H1N1 PA endonuclease in complex with SJ000986436
收藏Protein Data Bank Japan2023-10-25 更新2026-03-21 收录
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The crystal structure of the 2009 H1N1 PA endonuclease in complex with SJ000986436 Descriptor: 2-(2,6-difluorophenyl)-5-hydroxy-N-[2-(2-methoxypyridin-4-yl)ethyl]-6-oxo-3,6-dihydropyrimidine-4-carboxamide, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... Authors: Cuypers, M.G, Slavish, P.J, Jayaraman, S, Rankovic, Z, White, S.W. Deposit date: 2020-09-25 Release date: 2021-09-29 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential. Eur.J.Med.Chem., 247, 2023
创建时间：
2020-09-25
