RNA-Seq of Saccharomyces cerevisiae M28 strains with smooth and filigreed colony morphology, tissue invasiveness, differential immune recognition, resistant or sensitive to trifluoroleucine, SYBARIS project.

Saccharomyces cerevisiae M28 strain has been shown to form either smooth or filigreed colonies, and in some cases to exhibit resistance to trifluoroleucine. RNA-sequencing was used to analyse differences in the gene expression profiles of smooth or filigreed, resistant or sensitive colonies from three tetrads. Possibly the results should hint at the connection between these phenotypes and yeast strains pathogenicity.