Glucocorticoid effect on mRNA translation in childhood acute lymphoblastic leukemia

ChEBI2013-12-03 更新2026-07-21 收录

白血病耐药机制

mRNA翻译调控

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-48680 数据链接链接失效反馈

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Glucocorticoid effect on mRNA translation in childhood acute lymphoblastic leukemia

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2013-12-03

Translational repression of the Drosophila nanos mRNA involves the RNA helicase Belle and RNA coating by Me31B and Trailer hitch

果蝇生物学

mRNA翻译调控

The maternal mRNA nanos is required for anterior-posterior patterning in the early Drosophila melanogaster development. The nanos-mRNA is translationally repressed and deadenylated during the first tw

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Crystal structure of the double mutant (R39Q/D52N) of the full-length NT5C2 in the active state

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白血病耐药机制

Crystal structure of the double mutant (R39Q/D52N) of the full-length NT5C2 in the active state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cytosolic purine 5'-nucleotidase, MAGNESIUM ION, ... Authors: For

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RGG motif-containing Scd6/LSM14A proteins regulate the translation of specific mRNAs in response to hydroxyurea-induced genotoxic stress

基因毒性应激响应

mRNA翻译调控

RGG motif-containing proteins are the second largest group of RNA-binding proteins. Here, we identify a unique and conserved role of yeast Scd6 and its human ortholog LSM14A in hydroxyurea (HU)-mediat

NIAID Data Ecosystem20

Transcriptome-wide analysis of RNA N6-methyladenosine in Adriamycin-resistant acute myeloid leukemia cells

白血病耐药机制

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N6-Methyladenosine (m6A) is the most abundant post-transcriptional modification in eukaryotes, the imbalance of which is reported to be associated with various pathological processes, including drug r

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Data_Sheet_1_Acute Myeloid Leukemia Chemo-Resistance Is Mediated by E-selectin Receptor CD162 in Bone Marrow Niches.PDF

白血病耐药机制

肿瘤微环境靶向治疗

The interactions of leukemia cells with the bone marrow (BM) microenvironment is critical for disease progression and resistance to treatment. We have recently found that the vascular adhesion molecul

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Glucocorticoid effect on mRNA translation in childhood acute lymphoblastic leukemia

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