Expression data from PTEN-deficient regulatory T cells

We used microarrays to assess transcriptional changes in regulatory T cells upon deletion of PTEN. Foxp3+ CD25+ or Foxp3+ CD25- cells were double-sorted from 3 individual healthy 7 week old mice to ov

NIAID Data Ecosystem30

miRNA expression in PTEN-deficient premalignant DP thymocytes. Mus musculus

T cell-specific deletion of PTEN induces premalignancy in CD4+ CD8+ (DP) immature T cells in the thymus, which progresses to the development of mature CD4+ T cell lymphomas in the lymph nodes and sple

NIAID Data Ecosystem20

Gene expression data from mouse regulatory T cells. Mus musculus

Intravenous Immunoglobulin (IVIg) is widely used as an immunomodulatory therapy. We have recently demonstrated that IVIg protects against airway hyper-reactivity (AHR) and inflammation in mouse models

NIAID Data Ecosystem10

Expression data from PTEN-deficient regulatory T cells. Mus musculus