Gene expression analysis of inositol hexakisphospahte kinase 1 (Ip6k1) knockout testes in juvenile mice

Ip6k1 knockout male mice are infertile and display a delay in the first wave of spermatogenesis. To understand the underlying basis of this delay, we compared the gene expression profiles of whole testes from 17 days postpartum (17dpp) and 26 days postpartum (26dpp) Ip6k1 wild type (Ip6k1+/+) and Ip6k1 knockout (Ip6k1-/-) mice. We observed deregulation of several biological processes in Ip6k1-/- testes compared with Ip6k1+/+ testes. Two biological replicates each of 17dpp and 26dpp Ip6k1+/+ and Ip6k1-/- mice.