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Personalized computer simulations of a NeoAva non-responder patient: comparison of standard and alternative schedules

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Figshare2017-09-03 更新2026-04-08 收录
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The videos show personalized computer simulation of a breast tumor portion under the combined effect of chemotherapy and anti-angiogenic treatment. The simulations corresponds to 12 weeks of therapy in a luminal non-responder patient of the NeoAva clinical trial using standard and alternative schedules. Cancer, stroma cells and oxygen tension are shown. To produce the simulations we use a multiscale pharmacokinetic and pharmacodynamic model informed by individual, multisource clinical data, including histological, molecular and magnetic resonance imaging data. See reference below.

提供机构:
Xiaoran Lai
创建时间:
2017-09-03
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