Crystal Structure of the first bromodomain of human BRD4 in complex with Alprazolam
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Crystal Structure of the first bromodomain of human BRD4 in complex with Alprazolam Descriptor: 1,2-ETHANEDIOL, 8-chloro-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine, Bromodomain-containing protein 4 Authors: Filippakopoulos, P, Picaud, S, Felletar, I, Fedorov, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2011-10-11 Release date: 2011-11-23 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family. Bioorg.Med.Chem., 20, 2012
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2011-10-11
