Exploring Adsorption Performance of Functionalized Mesoporous Silicas with a Different Pore Structure as Strong Cation-Exchange Sorbents for Solid-Phase Extraction of Atropine and Scopolamine

This database includes information on the optimal parameters for mass spectrometry detection in MRM mode for the analysis of atropine and scopolamine using the UHPLC-TQ-MS/MS method developed in this work. It also details the textural properties and functionalization degree of the prepared functionalized mesoporous silicas. The Extracted Ion Chromatograms (EIC) of the most intense product ions and Mass Spectra (MS2) obtained for atropine and scopolamine are presented. Additionally, results from X-ray diffraction, transmission electron microscopy, scanning electron microscopy, nitrogen adsorption–desorption, Fourier-transform infrared spectroscopy, 29Si solid-state nuclear magnetic resonance spectroscopy, and elemental analysis are included. The different types of interactions that may occur between tropane alkaloids (TAs) and the MCM-41-SO3H sorbent used for solid-phase extraction are described. Finally, these materials were evaluated as sorbents for strong cation-exchange solid-phase extraction (SPE), determining their efficiency in the adsorption and desorption of tropane alkaloids (atropine and scopolamine).