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2019-02-11
相关数据集
Structural basis of the key residue W320 responsible for Hsp90 conformational change
The 90-kDa heat shock protein (Hsp90) is a homodimeric molecular chaperone with ATPase activity, which has become an intensely studied target for the development of drugs for the treatment of cancer,
Taylor & Francis Group2022-11-14 更新60
The cellular and molecular effects of the androgen receptor agonist, Cl-4AS-1, on breast cancer cells
Purpose: The androgen receptor (AR) has attracted attention in the treatment of breast cancer. Due to the undesirable side effects of AR agonists, attempts have been undertaken to develop selective AR
NIAID Data Ecosystem20
Data_Sheet_1_Silybin Prevents Prostate Cancer by Inhibited the ALDH1A1 Expression in the Retinol Metabolism Pathway.PDF
BackgroundSilybin was known to exert inhibition in prostate cancer, but the underlying mechanism remained largely unknown. This study was designed to find out the potential target of Silybin on prosta
NIAID Data Ecosystem20
Effects of ICI 182,780, an ERα and ERβ antagonist, and G-1, a GPER agonist, on autophagy in breast cancer cells
ABSTRACT Objective To investigate if ICI 182,780 (fulvestrant), a selective estrogen receptor alpha/beta (ERα/ERβ) antagonist, and G-1, a selective G-protein-coupled receptor (GPER) agonist, can pote
NIAID Data Ecosystem30
Calculated Maximal and EC50 Responses of AIS Mutations in HeLa Cells.
Values calculated by applying the 4-parameter curve fit algorithm available in SigmaPlot to multiple replicate experiments and represent Mean±S.E.M. All data are presented as absolute numerical measur
NIAID Data Ecosystem20
