FATP1 Exerts Variable Effects on Adipogenic Differentiation and Proliferation in Cells Derived from Muscle and Adipose Tissue

The effects of FATP1 on the differentiation and proliferation of adipocytes in five types of cells derived from muscle and adipose tissue and estimated the effects of FATP1 on intramuscular fat (IMF) deposition were investigated. <strong>Figure 1. </strong>The mRNA expression profile of FATP1 in tissues and cells as determined by RT-qPCR. <strong>Figure 2. </strong>The overexpression of FATP1 promotes lipid accumulation in buffalo myocytes. <strong>Figure 3. </strong>The overexpression of FATP1 promotes adipogenic differentiation in buffalo intramuscular preadipocytes. <strong>Figure 4. </strong>The overexpression of FATP1 does not affect adipogenic differentiation in buffalo subcutaneous preadipocytes. <strong>Figure 5. </strong>FATP1 promotes the proliferation of buffalo myocytes, intramuscular preadipocytes, and subcutaneous preadipocytes. <strong>Figure 6. </strong>FATP1 enhances the proliferation and promotes the adipogenic trans-differentiation of C2C12 cells. <strong>Figure 7. </strong>FATP1 inhibits both the proliferation and adipogenic differentiation of 3T3-L1 cells. <strong>Figure 8. </strong>The overexpression of FATP1 increases the intramuscular fat content in the mouse. <strong>Figure S1.</strong> The mRNA expression of <em>PPARG</em> and <em>CEBPA</em> in all the cells with adipogenic differentiation in figure 1.