Effect of green tea extract on systemic metabolic homeostasis in diet-induced obese mice; based on RNA-sequencing transcriptome profiles

We investigated the effect of green tea extract on phenotype characteristics and elucidated anti-obesity mechanism based on RNA-seq transcriptomic profiles in an obesity animal model. Overall design: Total RNA of epididymal adipose tissues and liver were obtained from normal diet, high-fat diet and green tea extract added high-fat diet-fed mice and mRNA expression-associated with lipid, and glucose metabolism was measured.