Induction of pathogenic Th17 cells by salt inducible kinase SGK-1 (SGK-1 KO)

ChEBI2013-03-07 更新2026-07-21 收录

Th17细胞

自身免疫性疾病

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-43956 数据链接链接失效反馈

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Induction of pathogenic Th17 cells by salt inducible kinase SGK-1 (SGK-1 KO)

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2013-03-07

CRAC channel controls the differentiation of pathogenic B cells in lupus nephritis

自身免疫性疾病

细胞分化调控

Systemic lupus erythematous (SLE) is a prototype of autoimmune disease. Lupus nephritis (LN) is one of the most serious complications of SLE. The development of autoreactive B cells and the production

NIAID Data Ecosystem60

Transcriptional profiling of human in vitro primed Th1, Th2, Th9 and Treg T cells. Transcriptional profiling of human in vitro primed Th1, Th2, Th9 and Treg T cells

T细胞亚群转录组学

自身免疫性疾病

To test whether human in vitro primed Th9 cells recapitulate the core pathogenic Th2 cell phenotype, we differentiated naïve T cells into Th1 (IL-12), Th2 (IL-4), Th9 (IL-4+TGF-β), and iTreg (TGF-β).

NIAID Data Ecosystem60

Single-cell transcriptional profiling of Th17 cells, differentiated in vitro for 48h [IL1B_IL6_IL23-48h-IL-17A/GFP+]

Th17细胞

自身免疫性脑脊髓炎

Extensive cellular heterogeneity exists within specific immune-cell subtypes classified as a single lineage, but its molecular underpinnings are rarely characterized at a genomic scale. Here, we use s

NIAID Data Ecosystem40

Draft genome sequencing of Clostridia bacterium UC5.1-2E1. Clostridia bacterium UC5.1-2E1

菌类基因组测序

Th17细胞

The genome sequences of the 20 Th17-cell-inducing strains were determined by the whole-genome shotgun strategy using an Ion PGM sequencer.

NIAID Data Ecosystem60

Title: An IL-23-STAT4 Axis Regulates Classical Dendritic Cell Expansion and Function in Experimental Autoimmune Encephalomyelitis

自身免疫性疾病

树突状细胞免疫调控

The signal transducer and activator of transcription 4 (STAT4) promotes protective immunity and autoimmunity downstream of pro-inflammatory cytokines including IL-12 and IL-23. In experimental autoimm

NIAID Data Ecosystem40

Induction of pathogenic Th17 cells by salt inducible kinase SGK-1 (SGK-1 KO)

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