Spaligner: Alignment Of Long Error-Prone Reads To Assembly Graphs
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This repository contains benchmarking datasets and scripts for the manuscript "SPAligner: alignment of long error-prone reads to assembly graphs". Graph representation of genome assemblies has been recently used in different applications — from gene finding to haplotype separation. While many of these applications are based on aligning DNA and protein sequences to assembly graphs, existing software tools for finding such alignments have important limitations. We present a novel SPAligner (Saint Petersburg Aligner) tool for aligning long reads to assembly graphs and demonstrate that it generates accurate alignments.
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2018-10-30
