Fecal metagenome dataset of 48 healthy women

Gut microbiota acts as an important complementary role in human health and is shaped by diverse factors including ethnicity, dietary pattern, and surrounding environmental factors. However, the effect of high-altitude environments on the human gut microbiota is rarely investigated. Herein, we characterized the gut microbiota of 30 and 18 healthy individuals living in sea level and high-altitude areas, respectively, using deep whole-metagenome shotgun sequencing of their fecal samples. The results in this pilot study provided pieces for understanding the underlying mechanisms of high-altitude geographic adaptation of the human gut microbiome.