Global reconstruction of DRD2 bound to LSD in complex with a mini-GoA and scFv16 obtained by cryo-electron microscopy (cryoEM)

Global reconstruction of DRD2 bound to LSD in complex with a mini-GoA and scFv16 obtained by cryo-electron microscopy (cryoEM) Descriptor: (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Kim, K, Gumpper, R.H, Fay, J.F, Roth, B.L. Deposit date: 2024-05-13 Release date: 2025-09-17 Last modified: 2025-10-15 Method: ELECTRON MICROSCOPY (2.32 Å) Cite: The polypharmacology of psychedelics reveals multiple targets for potential therapeutics. Neuron, 113, 2025