Transcriptome analysis of primary normal fibroblasts and matched cancer associated fibroblasts
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE196354
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To get an insight into the mechanisms for CAF-supported metastasis in breast cancers, we performed RNA-sequencing (RNA-seq) analysis with seven pairs of primary NFs and CAFs.Gene set variation analysis (GSVA) showed significant upregulated expression of genes enriched with cancer metastasis-associated signaling pathways. Besides, we identified CAF signature genes, which have similar patterns in several of these primary CAFs. The mRNA profiles of seven pairs of primary normal fibroblasts and matched cancer associated fibroblasts
创建时间：
2022-12-09
