Residues from the active sites of β-glucosidases in direct contact with sector A positions.

The numbering of the sector A positions was based on the Sfβgly sequence. * identifies catalytic glutamic acids; p – indicates residues involved in the modulation of the pKa of the catalytic glutamic acids; bg – shows residues involved in the binding of the substrate glycone; abr – indicates residues that form the aglycone binding region. Data regarding the role of individual residues in substrate binding and catalysis were retrieved from the literature [5], [27], [28], [29], [9], [30]. β-Glucosidase from Spodoptera frugiperda Sfβgly; β-glucosidase from Thermus thermophilus (1UG6); β-glucosidase A from Paenibacillus polymyxa (1E4I); β-glucosidase Zmglu from Zea mays (1E56); β-glucosidase SbDhr from Sorghum bicolor (1V03); myrosinase from Sinapis alba (1E6S); Human cytosolic β-glucosidase (2ZOX);β-glucosidase from Trichoderma reesei (3AHY).