Mammary tumors in transgenic mice expressing constitutively active and C-terminally truncated variants of STAT5
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE15119
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资源简介：
Stat5 is a latent transcription factor that regulates essential growth and survival functions in normal cells. Constitutive activity of Stat5 and the involvement of its C-terminally truncated variant have been implicated in blood cell malignancies and mammary or breast cancer. To distinguish the individual contributions of the Stat5 variants to mammary tumorigenesis, global gene-expression profiling was performed on transgenic STAT5-induced tumors. Mammary tumors derived from transgenic mice carrying one of two Stat5 variants were collected for RNA extraction and hybridization on Affymetrix GeneChip® Mouse Genome 430A 2.0 array.
创建时间：
2020-03-25
