Inhibition by ATP regulates the activity of a CBASS antiphage nucleotide cyclase

Inhibition by ATP regulates the activity of a CBASS antiphage nucleotide cyclase Descriptor: CD-NTase, PHOSPHATE ION, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-4-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate Authors: McMahon, S.A, Gaskell-Mew, L, Wotherspoon, P, McQuarrie, S, Graham, S, Gloster, T.M, White, M.F. Deposit date: 2025-08-08 Release date: 2026-08-05 Last modified: 2026-08-12 Method: X-RAY DIFFRACTION (2.83 Å) Cite: Inhibition by ATP regulates the activity of a CBASS anti-phage nucleotide cyclase. Biochem.J., 483, 2026