CCDB_3632.jpg
收藏cellimagelibrary.figshare.com2023-05-31 更新2025-03-23 收录
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资源简介：
Tomogram of the immunological synapse between a cytotoxic T lymphocyte
(CTL, top) and a target cell (bottom). The microtubule organization
centre (MTOC) is polarized to the cell-cell contact site. The
electron-dense lytic granules are transported along the microtubules to
the synaptic cleft. Here they probably fuse with the membrane and
excrete the cytotoxic proteins that trigger the death of the target
cell.
细胞毒性T淋巴细胞（CTL，上方）与靶细胞（下方）之间免疫突触的断层扫描图像。微管组织中心（MTOC）向细胞间接触部位极化。致密的电子密度溶解颗粒沿着微管运输至突触间隙。在此，它们可能融合于细胞膜并与释放出触发靶细胞死亡的细胞毒性蛋白质。
提供机构：
Cell Image Library
