Human SARM1 TIR domain bound to NB-3-ADPRP
收藏Protein Data Bank Japan2023-10-25 更新2026-04-19 收录
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Human SARM1 TIR domain bound to NB-3-ADPRP Descriptor: NAD(+) hydrolase SARM1, [[(2~{R},3~{R},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-[4-[(1~{S})-1-[methyl-[2,2,2-tris(fluoranyl)ethylcarbamoyl]amino]ethyl]pyridin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate Authors: Bratkowski, M.A, Mathur, P. Deposit date: 2022-05-26 Release date: 2022-09-21 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Uncompetitive, adduct-forming SARM1 inhibitors are neuroprotective in preclinical models of nerve injury and disease. Neuron, 110, 2022
创建时间：
2022-05-26
