TA loci alter tolerance to antibiotics and hydrogen peroxide.

WT or a strain lacking all six TAs were grown in M9-Glucose until late log phase and then challenged for 2 hours with ampicillin (100 μg/mL), ciprofloxacin (0.2 μg/mL), hydrogen peroxide (1.25 mM), or pH 3.3. Results are shown as log10 survival after 2 hours of stress relative to wild type. Mean of > 3 independent experiments performed in triplicate are shown; error bars denote SEM. One way ANOVA compared to WT P < 0.05 (*), P < 0.0001 (***).