Genome regulation by long noncoding RNAs during amelogenesis. Genome regulation by long noncoding RNAs during amelogenesis

We conducted the genome-wide lncRNA and mRNA expression profiling using RNA samples extracted from rat incisor enamel organs, so as to refine the number of predicted gene targets for lncRNA regulators. Overall design: RNA sampels were obtained from the mandibular incisor enamel organs of 5 rats from three developmental stages-maturation, secretory and cervical loop. Gene expression profiling was done separately for each of the 15 RNA samples.