Let-7 mediates the pro-lymphangiogenic effect of melanosomes
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE218501
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资源简介:
Melanoma-derived melanosomes traffic mature let-7i to lymphatic endothelial cells, which mediate pro-lymphangiogenic phenotypic changes by the induction of type I interferon signaling. Further, transcriptome analysis upon treatments with melanosomes or let-7i reveal the enhancement of IFI6 expression in lymphatic cells. Evaluation of gene expression in HDLECs transfected with let-7i or a scrambled control miRNA using a microarray.
创建时间:
2023-02-25



