Let-7 mediates the pro-lymphangiogenic effect of melanosomes
收藏NIAID Data Ecosystem2026-03-14 收录
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资源简介：
Melanoma-derived melanosomes traffic mature let-7i to lymphatic endothelial cells, which mediate pro-lymphangiogenic phenotypic changes by the induction of type I interferon signaling. Further, transcriptome analysis upon treatments with melanosomes or let-7i reveal the enhancement of IFI6 expression in lymphatic cells. Evaluation of gene expression in HDLECs transfected with let-7i or a scrambled control miRNA using a microarray.
创建时间：
2023-02-25
